The use of liposome in clinical medicine first came to trial in the 1960s, and research and clinical trials that have since followed made sure that this amazing technological evolution can now be applied for both clinical therapy and in other aspect of life. However, the liposomal encapsulation technology (LET) is still in its early stages of development, with little information known to the wider public.
Unlike other methods like in the use of needles for injections, swallowing of tablets, capsules or even syrup where the drug or the substance has to directly pass through the body tissues that are not the direct target, leading to possible reactions, loss of concentration or even interfering with the normal body functions, this method of drug administration employs an ingenious solution to drug administration. In fact, clinical trials have proven that it is better way of treating racehorses without the need of needles or syringes.
LET in its simplest form describes a process of using a phospholipid membrane also known as liposome to encase a given amount of pharmaceutical compounds and sometimes herbs to protect them from degrading when passing through the gastrointestinal tract. It has an excellent transference capability, making it a preferred option, particularly for the providers of nutritional supplements, beauty products and the topical moisturizers.
Phospholipid liposome can withstand the effect of anyone radicals, especially the chemicals, the body dampness, the basic liquids, and the salts inside the digestive tract. The substance enclosed is therefore secured till it gets to the targeted tissue where the cell walls of the tissue cells open allowing the phospholipids and its content inside. The result is a superb method of drug therapy that has minimum impact to functionality of normal body system.
The technology is so effective since it stems from the ability of liposomes to penetrate the cell walls and most other infective microorganisms. This gives it a winning advantage against most of pathogenic infections. In recent research findings, it was established that only 5 grams of Vitamin C that is enclosed in liposome is as effective as up to 50 grams of the same that is administered directly without the liposome casing.
Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.
The introduction of phospholipids into the body also comes with its advantages, the most common one being its anti aging properties. This is through its ability to cut down on serum lipids, decrease bad cholesterol, increase good cholesterol, and amplify red blood cell fluidity, decrease platelet aggregation, and triglyceride. It is also known to boost immunity, memory quality, exercise tolerance and offers liver protection among several other benefits.
LET comes with a number of benefits, but it is still advisable to consider all other therapy alternatives available and come up with the best and most comprehensive method to administer drugs.
Unlike other methods like in the use of needles for injections, swallowing of tablets, capsules or even syrup where the drug or the substance has to directly pass through the body tissues that are not the direct target, leading to possible reactions, loss of concentration or even interfering with the normal body functions, this method of drug administration employs an ingenious solution to drug administration. In fact, clinical trials have proven that it is better way of treating racehorses without the need of needles or syringes.
LET in its simplest form describes a process of using a phospholipid membrane also known as liposome to encase a given amount of pharmaceutical compounds and sometimes herbs to protect them from degrading when passing through the gastrointestinal tract. It has an excellent transference capability, making it a preferred option, particularly for the providers of nutritional supplements, beauty products and the topical moisturizers.
Phospholipid liposome can withstand the effect of anyone radicals, especially the chemicals, the body dampness, the basic liquids, and the salts inside the digestive tract. The substance enclosed is therefore secured till it gets to the targeted tissue where the cell walls of the tissue cells open allowing the phospholipids and its content inside. The result is a superb method of drug therapy that has minimum impact to functionality of normal body system.
The technology is so effective since it stems from the ability of liposomes to penetrate the cell walls and most other infective microorganisms. This gives it a winning advantage against most of pathogenic infections. In recent research findings, it was established that only 5 grams of Vitamin C that is enclosed in liposome is as effective as up to 50 grams of the same that is administered directly without the liposome casing.
Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.
The introduction of phospholipids into the body also comes with its advantages, the most common one being its anti aging properties. This is through its ability to cut down on serum lipids, decrease bad cholesterol, increase good cholesterol, and amplify red blood cell fluidity, decrease platelet aggregation, and triglyceride. It is also known to boost immunity, memory quality, exercise tolerance and offers liver protection among several other benefits.
LET comes with a number of benefits, but it is still advisable to consider all other therapy alternatives available and come up with the best and most comprehensive method to administer drugs.
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